![]() ![]() Today polyunsaturated fat in the diet is encouraged all over the world for its hypocholesterolemic effect. Polyunsaturated fat intake could not lower the serum cholesterol level in ascorbate deficiency. ![]() Liver microsomal cytochrome P-450 level was found to be low in ascorbate deficient animals. Elevation in serum and liver cholesterol and triglyceride along with depression in cholesterol oxidation and 7 alpha-hydroxylation in liver was observed in unsaturated fat fed guineapigs with ascorbate deficiency. Experimental animals were made chronic ascorbic acid deficient by allowing oral intake of 0.5 mg ascorbic acid/day/animal. Interrelationship of dietary lipids and ascorbic acid with hepatic enzymes of cholesterol metabolic pathway.Įffect of unsaturated and saturated fats on cholesterol metabolism was studied in ascorbate sufficient and deficient guineapigs. A total of one hundred and sixty (n= 160) parcipants, males, and females within the age range of 18-50 years (Mean age = 29.29± 8.74) were used for this study. ![]() This study was carried out to determine the effect of combined intake of Garcinia kola and Ascorbic acid on Intraocular pressure (IOP) of normotensive Nigerians. Effect of Combined Intake of Garcinia Kola and Ascorbic Acid on. ![]()
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